HGH 10UI

Recombinant Human Growth Hormone (rHGH) is a 191-amino acid single-chain polypeptide produced through recombinant DNA technology, structurally identical to the endogenous human growth hormone secreted by somatotroph cells in the anterior pituitary gland. This 24 IU (8 mg) variant is intended for comprehensive research into growth signaling pathways, cell proliferation, IGF-1 axis modulation, and metabolic regulation. HGH exerts its biological effects through binding to the growth hormone receptor (GHR), a member of the type I cytokine receptor superfamily, triggering JAK2-STAT5 signaling cascades that regulate gene transcription in target tissues. Research applications encompass studies on protein synthesis and nitrogen retention, lipolysis through hormone-sensitive lipase activation, chondrogenesis and longitudinal bone growth, hepatic IGF-1 and IGFBP-3 production, immune cell proliferation and thymic function, and glucose metabolism through insulin antagonism. The 10 IU format is suitable for standard-duration research protocols and pilot studies.