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</html><thumbnail_url>https://synerium.info/wp-content/themes/synerium-theme/assets/images/hero-vial.png</thumbnail_url><thumbnail_width>600</thumbnail_width><thumbnail_height>277</thumbnail_height><description>AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is an AMP analogue that activates AMPK, the master cellular energy sensor. Widely regarded as an exercise mimetic, AICAR induces gene expression programs associated with endurance training including mitochondrial biogenesis (PGC-1&#x3B1;), fatty acid oxidation, and fiber-type switching toward oxidative phenotype. Research applications span metabolic disease, muscle biology, and exercise physiology.</description></oembed>
